Claimed effect · TB-500

Does TB-500 help with cardiac repair?

D
Grade D — no human evidenceNone · effect size: not measurable
Short answerNo human evidence. As of 2 September 2026, only none exist for TB-500 for cardiac repair. Mouse and pig infarct models only.

What the studies show

Mouse and pig infarct models only.

Animal studies, cell studies, or anecdotes only. This is where almost every viral peptide sits. Promising and proven are different words for a reason.

In context

TB-500 is a synthetic fragment of thymosin beta-4, a protein involved in cell migration and wound repair. Full-length thymosin beta-4 has been through phase 3 trials — as an eye drop for dry eye disease, with mixed results and no approval. The injected use people buy it for, for tendon and muscle injury, has never been tested in a completed human trial. It is banned in sport and not approved anywhere.

TB-500 is not approved. Legal status differs by country — see the regulation section or the jurisdiction pages.

Questions

Is TB-500 proven to help with cardiac repair?
No. There is no human evidence for it (None); the claim rests on animal or cell studies and LYO grades it D.
What studies are behind the grade?
Mouse and pig infarct models only.
Is TB-500 approved for this?
No. TB-500 is not approved; it is not an approved medicine for any indication in the jurisdictions LYO covers.

Other outcomes for TB-500

Reviewed 2 September 2026. Grades count human evidence only; see how LYO grades. Not medical advice. Correct this page →