Definition
A family of receptors activated by melanocyte-stimulating hormone. MC1R drives pigmentation, which is why melanotan tans; MC4R sits in the brain's appetite and arousal circuits, which is why bremelanotide (PT-141) is approved for low sexual desire in premenopausal women. Nausea comes with the territory.
Where it matters on LYO
- APT-1412 phase 3 RCTs (n=1,267)
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